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Targeted Nanoparticle Delivery Across the Blood-Brain Barrier

2025-04-28 - 2025-04

Researchers at Oregon State University have developed dual peptide-functionalized polymeric nanocarriers capable of crossing the blood-brain barrier. This advancement enables targeted delivery of anti-inflammatory IRAK4 inhibitors to the hypothalamus in mice, significantly improving treatment outcomes for cancer cachexia—a condition causing severe weight and muscle loss. The approach resulted in a 94% increase in food intake and better retention of body weight and muscle mass. This technology holds promise for treating other neurological disorders such as Alzheimer's disease, Parkinson’s disease, and multiple sclerosis.

Self-Assembling Injectable Implants for Long-Term Drug Release

2025-04-25 - 2025-04

Scientists have developed a novel contraceptive implant administered via injection that self-assembles in the body, potentially offering long-term drug delivery without surgical procedures. In rat models, the implant sustained drug release for at least 97 days. This method, involving micro-crystals of synthetic progesterone in a water-resistant solvent, could be adapted for other treatments such as HIV, tuberculosis, schizophrenia, and chronic pain, especially in regions with limited medical infrastructure.

Freeze-dried exosomes could transform drug delivery and storage

2025-04-19 - 2025-04

The Gourdie laboratory had a problem of its own making. The lab at the Fralin Biomedical Research Institute at VTC has spent years exploring how microscopic containers naturally found in raw cow's milk—called exosomes—can be used to carry medicine through the body.

Agno Pharma’s Particle Sciences, Inc. Achieves ISO 13485:2016 Certification

2025-04-17 - 2025-04

Agno Pharma recently announced its subsidiary, Particle Sciences, Inc., has earned ISO 13485:2016 certification from National Quality Assurance, U.S.A. (NQA). This achievement underscores Particle Sciences’

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Targeted Nanoparticle Delivery Across the Blood-Brain Barrier

Self-Assembling Injectable Implants for Long-Term Drug Release

Freeze-dried exosomes could transform drug delivery and storage

Agno Pharma’s Particle Sciences, Inc. Achieves ISO 13485:2016 Certification

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