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Anaemia

2025-04-25 - 2025-04

Anaemia is a condition in which the number of red blood cells or the haemoglobin concentration within them is lower than normal. It mainly affects women and children.

Anaemia occurs when there isn’t enough haemoglobin in the body to carry oxygen to the organs and tissues.

In severe cases, anaemia can cause poor cognitive and motor development in children. It can also cause problems for pregnant women and their babies.

Anaemia can be caused by poor nutrition, infections, chronic diseases, heavy menstruation, pregnancy issues and family history. It is often caused by a lack of iron in the blood.

Anaemia is preventable and treatable.

In many low- and lower-middle income settings, the most commonly- recognized causes of anaemia are iron deficiency and malaria.

Noida’s Child PGI plans drone-based blood transport pilot

2025-04-23 - 2025-04

The proposal, if approved, aims to address the persistent issue of timely blood availability in remote areas, especially for kids with serious blood disorders
As part of the proposed project, hospitals located within a 100-kilometre radius of the Child PGI will receive blood via drones. Currently, many families from rural areas have to travel long distances to reach Child PGI in Noida because local hospitals don’t always have blood when needed. This is a serious problem for children suffering from diseases like thalassemia and sickle cell anemia, who often need regular blood transfusions, said officials.

Dr Seema Dua, in charge of the blood bank at Child PGI, said that the project is currently in its preliminary stage. “We have submitted a proposal to the Indian Council of Medical Research (ICMR) and are currently awaiting approval, including necessary funding and other support. Once we get the green signal, we plan to begin with a pilot phase where blood units will be delivered via drones to hospitals within a 100km radius,” she added.

Sickle cell experts worry as CDC’s Division of Blood Disorders staff put on leave

2025-04-19 - 2025-04

Sickle cell disease experts are worried that recent staffing changes at the Centers for Disease Control and Prevention will impact a program that collects data about the genetic disease and how it impacts more than 100,000 patients across the country.

In March, the Trump administration announced sweeping changes at the Department of Health and Human Services, including the U.S. Centers for Disease Control and Prevention. In a public post, HHS said that the move will streamline the department’s processes and save taxpayers $1.8 billion per year through downsizing the department’s workforce.

“We aren’t just reducing bureaucratic sprawl. We are realigning the organization with its core mission and our new priorities in reversing the chronic disease epidemic,” HHS Secretary Robert F. Kennedy Jr. said, according to the statement. “This Department will do more – a lot more – at a lower cost to the taxpayer.”

Nearly all of the staff at the Division of Blood Disorders and Public Health Genomics at the CDC were placed on administrative leave, according to the National Bleeding Disorders Foundation and experts familiar with the division’s staff.

Doctors and public health experts say the division oversees programs that more than one million people in the U.S. with inherited bleeding disorders like thrombosis, thrombophilia, hemophilia, sickle cell disease and thalassemia rely on. They said the abrupt changes to the division happened without clear communication regarding plans for the future of the division’s programs.

The American Society of Hematology and 95 national and state organizations representing patients sent a letter to the HHS secretary urging him to reinstate the Division of Blood Disorders and Public Health Genomics.

Supercharged mitochondria spark aging-related blood disorders

2025-04-17 - 2025-04

As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give the cells a growth advantage, laying the foundation for developing serious health conditions. Now, scientists at The Jackson Laboratory (JAX) have not only discovered the mechanism that fuels their unchecked growth but have also found a way to stop it.
This mutation allows the cells to make copies of themselves more readily than normal and creates fertile ground for the development of clonal hematopoiesis, a condition that dramatically increases the risk of heart disease, blood cancers, and other illnesses.

Although clonal hematopoiesis develops silently with age—more than half of all 80-year-olds are estimated to be affected by the condition—the mutated blood stem cells can produce inflammatory molecules that disrupt blood production and weaken the immune system.

"This work gives us a new window into how and why blood stem cells change with age and how that sets up an increased risk of diseases like cancer, diabetes, and heart disease," said Trowbridge. "It also points toward a new opportunity to intervene and potentially prevent age-associated conditions not only in the blood but everywhere the blood touches."

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Anaemia

Noida’s Child PGI plans drone-based blood transport pilot

Sickle cell experts worry as CDC’s Division of Blood Disorders staff put on leave

Supercharged mitochondria spark aging-related blood disorders

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