Scientific Program | Neurology | Neuroscience | Brain

Puberty Brain Shift May Explain Autism in Genetic Disorder

2025-04-14 - 2025-04

Researchers have identified changes in brain connectivity before and after puberty that may explain why some children with chromosome 22q11.2 deletion syndrome are more susceptible to autism and schizophrenia. Using brain imaging in both mice and humans, the study found that brain regions involved in social behavior were hyperconnected in childhood but under-connected after puberty.

These shifts appear linked to changes in synaptic structure, particularly a sharp loss of dendritic spines after puberty. Inhibiting a key protein, GSK3-beta, partially restored connectivity in mice, highlighting a potential therapeutic target for neurodevelopmental disorders.

Key Facts:

Connectivity Flip: Brain regions in 22q deletion were overconnected before puberty, under-connected after.
Synaptic Link: Post-pubertal drop in dendritic spines correlated with disrupted social behaviors.
Targetable Pathway: Inhibiting GSK3-beta restored connectivity and spine density in mice.

A Grain of Brain, 523 Million Synapses, and the Most Complicated Neuroscience Experiment Ever Attempted

2025-04-15 - 2025-04

A team of over 150 scientists has achieved what once seemed impossible: a complete wiring and activity map of a tiny section of a mammalian brain.

This feat, part of the MICrONS Project, rivals the Human Genome Project in ambition and scope, using cutting-edge AI, microscopy, and teamwork to map over 200,000 brain cells and millions of synapses. Among many revelations, researchers uncovered surprising new rules for how inhibitory neurons selectively influence others, providing insight into how thought, memory, and disorders like Alzheimer’s might emerge from cellular interactions. This achievement opens the door to a new era in brain science and medical breakthroughs.

Cracking the Brain’s Wiring Code
From a tiny piece of brain tissue no larger than a grain of sand, scientists have achieved what once seemed impossible: creating a detailed, functional wiring diagram of part of the brain. In 1979, molecular biologist Francis Crick famously predicted it would be “[impossible] to create an exact wiring diagram for a cubic millimeter of brain tissue and the way all its neurons are firing.” But now, after seven years of work, more than 150 scientists and researchers from around the world have brought that vision much closer to reality.

Neurological Disorder Diagnostics Market to Witness Massive Growth by 2032 | Siemens Healthineers, Koninklijke Philips N.V., General Electric Company

2025-04-16 - 2025-04

Latest Qualitative Research Report on the Neurological Disorder Diagnostics Market 2025, published by Coherent Market Insights, provides valuable insights into both regional and global markets projected to grow in value from 2025 to 2032. The comprehensive research explores into the evolving Market's dynamics, value chain analysis, prominent investment areas, competitive landscape, drivers and constraints, regional outlook, and key market segments. It's also provides the industry overview with growth analysis and historical & futuristic cost, Statistics, revenue, demand and supply data (as applicable). Additionally, the report highlights effective strategies and opportunities within the market, providing essential guidance for industry professionals, policymakers, stakeholders, investors, and newcomers. This will help them identify key strategies, explore market size opportunities, and gain a competitive advantage in the Neurological Disorder Diagnostics Market.

International Conference on Neurology and Neuroscience

useful links

Latest News

Puberty Brain Shift May Explain Autism in Genetic Disorder

A Grain of Brain, 523 Million Synapses, and the Most Complicated Neuroscience Experiment Ever Attempted

Neurological Disorder Diagnostics Market to Witness Massive Growth by 2032 | Siemens Healthineers, Koninklijke Philips N.V., General Electric Company

neuroscience@confmeets.net

support@confmeets.net

+44-7477-467410